RECENT FEATURE ARTICLES
Back at the coalface: a clinical virologist and the COVID emergency
Response to the current coronavirus pandemic has seen many retired personnel return to the clinical laboratory bench to help facilitate realisation of testing targets. Such altruistic action does reintroduce the returnee to the reality of change.
Microbiology testing networks: are they of value and fit for purpose?
Valerie Bevan looks at how microbiology testing networks have changed over the past 80 years, and how reflecting on this, and lessons from the current pandemic, might inform our response to future epidemics/pandemics.
Histologists and molecular biology: meet the next generation
One of the two recognised early pathology disciplines, histopathology now combines modern practical laboratory techniques with sophisticated molecular biology methods,both of which facilitate the application of personalised medicine.
Plasma viscosity in COVID-19 disease: a vital monitoring role.
Establishing the diagnostic and prognostic value of measuring plasma viscosity in patients suspected or confirmed as having COVID-19 is currently underway in several UK hospitals. This article provides an overview of progress in research and practice
Fusobacterium infection: is Lemiérre’s disease the tip of an iceberg?
Is Fusobacterium necrophorum an underrated anaerobic pathogen, and could Lemiérre’s disease be prevented by earlier treatment of sore throat? Here, Mike Wren looks at the available evidence and illustrates some of the issues in two short case studies
Reducing parasitic disease in Africa: multinational research
Cutting-edge flow cytometry is underpinning a pioneering multinational research initiative designed to transform the lives of those suffering from leishmaniasis, a disfiguring and potentially life-threatening parasitic disease.
Pandemic coronavirus: an overview of SARS-CoV-2 and COVID-19 disease
Pathology faces a major challenge to detect the new coronavirus, and to provide laboratory support to COVID-19 patients. Sarah Pitt provides an overview of the virology, epidemiology and laboratory diagnosis of this latest agent of disease.
Antimicrobial efficacy and lack of resistance to silane quaternary com
Does the ‘entourage effect’ explain the increase in antimicrobial efficacy and lack of resistance seen with fifth-generation silane quaternary compounds? Here, Andrew Kemp provides an overview of the development and use of such agents.
Automated algorithms for FVIII and FIX: inhibitor detection in haemophilia
The detection and monitoring of haemophilia remains a challenging process for laboratories; however, the introduction of testing algorithms is set to improve the quality and consistency of results while freeing staff time.
Coagulation profiler: proof-of-concept testing and development
Benson Viscometers is developing a novel device that can determine the clotting profile of a blood sample. Furthermore, the company also aims to develop the point-of-care capabilities of this device.
Artificial intelligence and digital pathology: a look to the future
As the pathologist workforce shrinks and workload increases, laboratory medicine is beginning to adopt advanced technology and robust AI solutions. Nathan Buchbinder and Scott Rayburn explain how digital solutions can change practice in pathology and the life sciences.
Group B Streptococcus: what are we missing in the newborn period?
Group B Streptococcus is the most common cause of severe infection in newborn babies in the UK. Despite a risk-based prevention strategy for early-onset infection, in place since 2002, rates have increased significantly.
Disinfectants and hand sanitisers: a new test of efficacy against viruses
Do hand sanitisers really work against viruses? Andrew Kemp and colleagues introduce a new methodology for testing the efficacy of disinfectants and sanitisers on surfaces and on the skin against viral isolates.
Total bile acids testing: fifth-generation method in cholestasis of pregnancy
The advanced enzyme cycling method for bile acids offers increased sensitivity and precision when compared to traditional enzymatic tests, as illustrated by its use in obstetric cholestasis diagnosis and monitoring.
Veterinary pathology in Kenya: charismatic and not so charismatic creatures
In terms of scope and geography, veterinary pathology in the field is an activity of wide horizons. In this review of a visit to Kenya, Margaret and John Cooper describe how they are committed to training the next generation of veterinary workers in East Africa.
Surgical site infections: a need to galvanise efforts to reduce occurrence
Surgical site infection continues to be a major source of concern to patients and the multidisciplinary teams involved in surgery. Sadly, however, evidence-based practice to reduce such infections is often slow to be implemented, as Kate Woodhead explains.
Cell-free DNA and testing for cancer: a brief look in the literature
Recent national news focused on the role that cell-free DNA (cfDNA) testing may have in detecting many different types of cancer. Here, a small selection from the current literature highlights future possibilities and some potential problems.
Coronaviruses in the literature: another beast from the Orient
Over the past decade, infections caused by coronaviruses have resulted in severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome. Now, a new coronavirus is causing worldwide concern, and is exercising the research community, as this small selection of very recently published articles illustrates.
A glass act: adhesion and clarity in the modern histopathology laboratory
Although often taken for granted, modern glass microscope slides, their characteristics and features can have an impact on test performance, diagnosis and laboratory workflow. Here, Mark Wilson looks at some of the features offered by Epredia products.
Clinical flow cytometry: advances in techniques and instrumentation
Clinical flow cytometry continues to feature in an eclectic range of applications in routine laboratory medicine and in the research environment. In addition to its use in haematology and immunology, flow cytometry has a cutting-edge role in investigating diverse biological processes, and the latest system developments offer innovation and increasing ease of use.
Upcoming Events
Pathology Horizons 2024
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18-20 April, 2024
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2 May 2024
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Thursday 16th May 2024
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Sheffield Hallam University, City Campus, Howard Street, Sheffield
24th May 2024
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