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Type 2 diabetes: proteins, oxidative status and stress, and biomarkers

Of the hundreds of millions of diabetes cases globally, 90% are estimated to be type 2 diabetes mellitus. Although T2DM is more common in adults, as obesity in children, teenagers and young adults has increased, so too has the incidence of T2DM.

Currently there is no cure for type 2 diabetes mellitus (T2DM), but it can often be managed through exercise, eating well and maintaining a healthy weight. If lifestyle changes are not enough, oral medications or insulin therapy may be necessary. Considerable work has been undertaken to research T2DM, as illustrated by work undertaken in the UK by groups in Lincoln and Wolverhampton,1 and also by researchers in India.2 Elsewhere, a group in Iran3 evaluated the effects of oligofructose-enriched inulin on T-cell subsets and their related cytokines, anthropometric and metabolic parameters in patients with T2DM and showed several beneficial effects of this approach on glycaemic control. More recently, studies have reviewed the role of biomarkers, metabolomics, proteomics and genomics in T2DM.4,5

Brief introduction to diabetes

Type 2 diabetes mellitus occurs when the body cannot properly use insulin to r

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Online
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IBMS Biomedical Science Congress 2022

International Convention Centre, Birmingham
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Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

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