MEASUREMENT UNCERTAINTY ARTICLES

In this sixth article in his series, Stephen MacDonald looks at the widespread use of semi-quantitative assays where more research and discussion is needed into how to apply statistical approaches to their measurements, and the impact that has on clinical decision-making.

In this further article in his series on measurement uncertainty, Stephen MacDonald moves on to look at bias, and considers its nature, detection, clinical and statistical significance, and correction.

In this fourth article in his series on measurement uncertainty, Stephen MacDonald moves on to look at some of the lesser discussed points that need to be considered when calculating imprecision and its contribution to combined uncertainty.

In this third article in his new series, Stephen MacDonald summarises some interesting highlights of the current understanding of analytical performance specifications and in particular how they are applied to measurement uncertainty.

With increased awareness of metrological traceability, both from an IVD manufacturer and end-user perspective, improvements in analytical methods are possible. In this second article in his new series on measurement uncertainty, Stephen MacDonald provides a detailed overview of the issues involved.

In this first of a series of articles, Stephen MacDonald returns to the topic of assessing measurement uncertainty in the clinical laboratory, and provides an update on the current situation and provides a taster of what will be covered in future articles.