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New haemostasis workflow solutions offer enhanced immunology testing

The CN-3000 and CN-6000 models from Sysmex are joined by the CN-3500 and CN-6500 systems to provide laboratories with advanced immunological testing capabilities, and connectivity of these systems by the intelligent Laboratory Automation solution.

Haemostasis testing has experienced a dramatic change over the last 50 years. Since the 1950s up to the early 1990s, coagulation tests were performed manually by many laboratories. Reagents were manufactured ‘in-house’ by the laboratory staff of larger hospitals processing animal or human brains in a batch-wise fashion. These reagents were then used in the respective coagulation test such as prothrombin time (PT), activated partial thromboplastin time (APTT) and other global coagulation tests. Equipped with a centrifuge, a stopwatch, a pipette, a water bath and a test tube, the laboratory staff used these ‘in-house’ reagents to determine the clotting capability of a patient sample.1

            In 1984, Sysmex Corporation released the CA-100, to standardise and optimise coagulation testing using scattered light for optical end-point clot detection. Through the 1990s, instruments were improved, enlarged and expanded so that not only coagulation tests but also colourimetric and immunoturbidimetric testing could be supported on the same platform, delivering higher productivity and workflow from an automated coagulation analyser. By the 1990s, reagents were improved through their production by reagent manufacturers providing a huge leap towards standardisation.

            The CS-Series family of Sysmex analysers was introduced by the CS-2000/2100i in 2006 and later with the additions of the CS-5100 in 2011 and CS-2400/2500 in 2014.

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