SARS-CoV-2 droplet digital polymerase chain reaction test

Bio-Rad provides a wide range of products for use in the support of COVID-19 diagnosis and confirmation, and offers a suite of molecular testing tools including Droplet Digital PCR (ddPCR) systems and the SARS-CoV-2 ddPCR test kit.

Update on Affimer reagent therapy for SARS-CoV-2 infection

Infectivity assays carried out by the Avacta Group in collaboration with the Centre for Virus Research at the University of Glasgow show that the company’s Affimer reagents prevent infection of human cells by a SARS-CoV-2 model virus.

Adapt and succeed in challenging laboratory times

The Royal Society reports that every £1 invested in medical research delivers a return equivalent of around 25 pence every year, forever. Here, Katie Gray explains how UK laboratories are remaining productive during the lockdown.

Danish robots assist in European testing for SARS-CoV-2 coronavirus

A Danish pipetting robot is automating coronavirus testing processes in European hospitals. The robot, called flowbot ONE, significantly reduces the time it takes for laboratories to produce results for patients potentially infected with SARS-CoV-2.

Safer ELISA antibody testing with convenient buffer removal

The SARS-CoV-2 pandemic has led to the development of novel RT-PCR-based tests to detect the virus. As the situation has progressed, serology tests are now needed to evaluate the immune response of patients, and assess immunity in the general public.

SARS-CoV-2 IgM and IgG detection from whole blood, serum and plasma

The ScheBo SARS-CoV-2 Quick is a combined immunochromatographic lateral-flow test for the simultaneous qualitative detection of SARS-CoV-2 IgM and IgG antibodies in whole blood, serum or plasma, with test results after 15 minutes.

SARS-CoV-2 kit for research into measuring the T-cell immune response

Oxford Immunotec has released the T-SPOT Discovery SARS-CoV-2 test kit. This could make a significant contribution to development of a tool to manage the current pandemic, and help nations come out of lockdown faster, safer and in a controlled manner

SARS-CoV-2 IgG antibody test now available in the UK and Europe

Beckman Coulter’s Access SARS-CoV-2 IgG assay is now available in markets accepting the CE mark. The company has shipped tests to more than 400 hospitals, clinics and laboratories in the USA, and has begun shipping to customers globally.

Cytokine testing for COVID-19 risk and treatment monitoring

An innovative method of monitoring treatment efficacy and recovery from COVID-19 has been unveiled by global diagnostics company Randox Laboratories. The test detects the presence of cytokines, and is performed on the company’s Biochip Technology.

Significant leap forward for SARS-CoV-2 detection

PCR Biosystems has launched qPCRBIO Probe 1-Step Virus Detect, a high-concentration 4x RT-qPCR kit designed specifically for ultrasensitive, high-throughput detection of viral RNA sequences, including SARS-CoV-2.

Hand sanitisers: do they work against SARS-CoV-2 coronavirus?

It seems bizarre that at the time of writing, we are into the fourth month of a viral pandemic, and yet only one of many available disinfectant and hand sanitiser chemistries had been tested against SARS-CoV-2 coronavirus. Andrew Kemp explains.

Set up heparin assay protocols quickly and remotely

The NHS has announced that heparin is to be trialled on critically-ill COVID-19 patients, putting more pressure on laboratories to set up new anti-Xa assay protocols. Stago UK is able to help remotely using its Connect.One data sharing middleware.

Three-dimensional model of SARS-CoV-2 in detail

As scientists around the world race to understand more about SARS-CoV-2, the virus responsible for COVID-19 disease, they are gaining increasing amounts of information about the viral components that make up the infectious particles.

Black and Asian groups are at higher risk of SARS-CoV-2 infection

Black and south Asian ethnic groups in England appear to be at higher risk of SARS-CoV-2 infection and COVID-19, as well as hospitalisation with the disease, according to new UK Biobank research.

Health and care staff recruited to vaccine trial in Glasgow

The University of Glasgow and NHS Greater Glasgow & Clyde (NHSGGC) are supporting the University of Oxford’s SARS-CoV-2 coronavirus vaccine trials in health and care staff. The collaboration is part of the University of Oxford’s Phase III of the trial, which involves assessing health and care staff living in Greater Glasgow and Clyde, who will be invited to take part in the trial if they are aged 18–55 years, healthy and have not been infected with SARS-CoV-2.

SARS-CoV-2 coronavirus: rabbit antibody discovery using single B-cell screening

Effective and reliable solutions to detect SARS-CoV-2 are urgently needed, and antibody-based serological assays are a sensitive way to diagnose infection. Dr Pei Liu (Senior Scientist, Antibody Department, GenScript) will lead a free webinar on 2 June 2020 (10.00 am EST [3.00 pm BST] and 1.00 pm EST [6.00 pm BST]). Click on this story to access the link to register.

Whole pathogen molecular controls for SARS-CoV-2 receive CE marking

CE marking has been granted to whole-pathogen quality controls for SARS-CoV-2, from global diagnostics company Randox Laboratories. The molecular controls are currently being used alongside the firm’s coronavirus tests, performed on its proprietary Biochip, as part of a nationwide UK testing programme.

Coronavirus sample collection kit manufacturing and supply contracts secured

EKF Diagnostics has secured new contracts for the manufacture and supply of a novel, patented sample collection device which allows SARS-CoV-2 coronavirus samples to be rapidly inactivated in the collection tube, avoiding contamination and preserving RNA without need for refrigeration. To support the increase in testing globally, a safe and easy sample collection and transport mechanism is essential, and this is provided by the PrimeStore MTM sample collection device.

Expansion of SARS-CoV-2 testing to include a total antibody test

Siemens Healthineers is expanding its infectious disease testing capabilities to aid in the SARS-CoV-2 pandemic. Recognising the critical need for accurate diagnostic testing, the company has developed a laboratory-based total antibody test to detect the presence of SARS-CoV-2 antibodies in blood.

Microchip RT-PCR coronavirus detection system announced

The current pandemic has created a demand for test kits that can be run with less amount of reagents while generating faster test results. Lumex Instruments’ microchip real-time PCR analyser, AriaDNA, by detecting SARS-CoV-2, has proven its ability to meet this demand. The Microchip RT-PCR coronavirus detection system based on AriaDNA can test up to seven patient samples in one run, which takes less than an hour, with low reagent consumption.