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Antigen detection of SARS-CoV-2 variants

All ViroStat COVID-19 monoclonal antibodies are validated to react with the nucleocapsid of common variants circulating, including UK B.1.1.7, South Africa B.1.351 and Brazil P.1, ensuring that the variants will be detected with these antibodies.

Variants of SARS-CoV-2 have evolved due to mutations in the spike protein; however, most antigen detection tests target the nucleocapsid of the virus with the use of antibody pairs. While the nucleocapsid is relatively conserved in comparison to the spike protein, mutations also occur in the nucleocapsid. If the antibody pair used for detection now fails to bind to this antigen because of a mutation, then this could result in a false-negative test result.

Go to the ViroStat website for further information or to download the data sheets for these antibodies.

www.virostat-inc.com

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Upcoming Events

Near Miss Events and Incident Investigation webinar

Online
19 May 2021

Lab Innovations 2021

NEC, Birmingham
3-4 November 2021

IBMS Biomedical Science Congress 2022

International Convention Centre, Birmingham
14-17 March 2022

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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