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Sickle cell disease: papers with a genetic focus in the literature

he recent reporting in the media of one man’s gene editing treatment to reverse the effect of his sickle cell disease has thrust this condition into the limelight. The following are examples of open-access coverage of sickle cell genetics in the current literature.

Techniques for the detection of sickle cell disease: a review

Arishi WA, Alhadrami HA, Zourob M. Micromachines (Basel) 2021; 12 (5): 519. doi: 10.3390/mi12050519.

Sickle cell disease (SCD) is a widespread condition caused by a mutation in the beta-globin gene that leads to the production of abnormal haemoglobin – haemoglobin S. The inheritance of the mutation could be homozygous or heterozygous combined with another haemoglobin mutation.

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