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Neisseria gonorrhoeae: an STI that has developed resistance mechanisms to antimicrobials

Last year, over 85,000 gonorrhoea diagnoses were reported in England, the highest number since records began in 1918. Here, Pathology in Practice Science Editor Brian Nation compiles a selection of current research interest focusing on AMR in this sexually transmitted infection.

Neisseria gonorrhoeae Antimicrobial Resistance: The Future of Antibiotic Therapy

Raccagni AR, Ranzenigo M, Bruzzesi E, Maci C, Castagna A, Nozza S. J Clin Med. 2023 Dec 18; 12 (24): 7767. doi: 10.3390/jcm12247767.

The growing threat of antibiotic-resistant Neisseria gonorrhoeae, which causes gonorrhoea, presents a current public health challenge. Over the years, the pathogen has developed resistance to different antibiotics, leaving few effective treatment options. High-level resistance to key drugs, including ceftriaxone, has become a concerning reality. 

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