Sponsors

Post-transcriptional gene regulation and the role of microRNAs

For their discovery of microRNAs, the Americans Victor Ambros and Gary Ruvkun received this year’s Nobel Prize in Physiology or Medicine. Here, Pathology in Practice Science Editor Brian Nation compiles a selection of current research interest in these tiny RNA molecules that play a crucial role in health and disease.

MicroRNA-206 in human cancer: Mechanistic and clinical perspectives

Bahari Khasraghi L, Nouri M, Vazirzadeh M et al. Cell Signal. 2023 Jan; 101: 110525. doi:10.1016/j.cellsig.2022.110525.

MicroRNAs (miRNAs), small non-coding RNAs approximately 20-25 nt in length, play important roles via directly binding to the corresponding 3’ UTR of target mRNAs. Recent research has shown that miRNAs cover a wide range of diseases, including several types of cancer. 

Log in or register FREE to read the rest

This story is Premium Content and is only available to registered users. Please log in at the top of the page to view the full text. If you don't already have an account, please register with us completely free of charge.

Latest Issues

Introduction to bone marrow trephine

Online
9 December, 2025

Fresh muscle biopsies webinar

Online
11 December, 2025

POCT Innovators - The power to disrupt through diagnostics

National Army Museum, Chelsea, London
15 December, 2025

RSM / Path Soc 2026 Winter Meeting

The Royal Society of Medicine, 1 Wimpole St, London, W1G 0AE
20 - 21 January, 2026

BIVDA Regulatory Affairs Seminar

Grand Hotel, Birmingham
10 - 11 February, 2026