RECENT FEATURE ARTICLES
Potential impacts of the EU IVD-Regulation on clinical flow cytometry.
Maurizio Suppo provides an overview of the new EU IVD-Regulation and elaborates on how EU authorities will regulate the vast majority of the laboratory-developed tests currently performed across Europe on a daily basis.
IVD Regulation changes in the United Kingdom in the post-Brexit era.
Doris-Ann Williams discusses how IVDs will be regulated in a newly independent UK after being regulated under the IVD Directive for the past 20 years, and the effects this may have on industry and clinical laboratories in the UK.
Non-gynaecological cytopathology: the importance of preparation
Beverley Crossley provides an overview of the techniques applicable to the various sample types encountered in routine practice.
Overcoming challenges in ketone testing: from diabetes to sepsis
The detection and monitoring of patients suffering from ketoacidosis continues to increase the laboratory medicine workload. Here, Randox Laboratories examines the issues and illustrates the scope of the problem.
Fighting AMR in the era of SARS-CoV-2 and COVID-19 disease
The threat posed by antimicrobial resistance was high on the agenda at the FIS/HIS International online conference, where Evelina Tacconelli called for action. Louise Frampton reports on proceedings.
Commerce and COVID-19: a need for reconfiguration and transformation
The in vitro diagnostics industry has been at the forefront of the fight against SARS-CoV-2. Here, Mark Reed provides a commercial perspective and overview of the unprecedented times experienced over the past 12 months.
Method comparison studies: an introduction to acceptability criteria
In this third article in his series on method comparisons, Stephen MacDonald moves on to focus on what differences are expected and acceptable, and what other factors need further investigation before implementation of an assay.
Innovative haemostasis systems for routine and special testing
The CN-Series of analysers from Sysmex has now undergone multi-centre validation and verification work in the UK ahead of global introduction in 2021. Here, the company introduces the equipment and its various hardware and software features.
Barrett’s metaplasia: subtyping, stem cells and receptors
Gastroesophageal reflux disease (GERD) is a common condition which, if left untreated, may result in intestinal metaplasia, a premalignant condition that occurs in the upper gastrointestinal tract.
Hepatology: researching cirrhosis, HBV and intestinal microflora
A report on the impact of COVID-19 on patients with decompensated cirrhosis, along with an overview of HBV and the role of intestinal microflora in alcohol-related liver disease.
Hepatitis B virus: a small selection of research in the literature
Hepatitis B, a potentially life-threatening liver infection caused by the hepatitis B virus (HBV), is a major global health problem. It can cause chronic infection and puts people at high risk of death from cirrhosis and liver cancer.
Plasma viscosity: accuracy, precision and suitability – who wants it?
The diagnostic and prognostic value of plasma viscosity has been highlighted in patients suspected or confirmed as having COVID-19, but its use in other areas of UK medical practice has gained clinical acceptance over the past seven decades.
Releasing pressure on pathology services: RFID technology has the key
With the NHS continuing to struggle as it responds to the current SARS-CoV-2 pandemic and the effects that COVID-19 disease is having on a heavy workload, Gillian Ewers examines the advantages that RFID and a transport and tracking system offer.
Biomedical laboratory Science: an international perspective
The International Federation of Biomedical Laboratory Science has a global responsibility to support, advance and promote good scientific laboratory practice and education. Here, new IFBLS President Alan Wainwright provides an overview.
Reducing the COVID-19 burden: diagnostics and the patient pathway
Tony Cambridge looks at a changing healthcare landscape as the service continues to respond to the ongoing coronavirus pandemic, and considers the important role of point-of-care tests and combination testing.
Diagnostic testing in cases of SARS-CoV-2 adverse outcomes
Severe cases of COVID-19 disease exhibit a range of immunological, kidney, liver and heart complications that require laboratory investigation. Randox Laboratories provides an overview and looks at quality control and assessment of testing.
Pathology partnership strengthened during SARS-CoV-2 pandemic
Award-winning NHS partnership SWLP has adopted equipment from Beckman Coulter’s AutoMate 2500 family of sample processing systems, which has streamlined pre- and post-analytical processes to help gain optimal performance and use of resources.
Point-of-care testing aids decision-making in GP-based assessment hub
A study in primary care demonstrates how testing can avoid unnecessary hospital admissions and improve patient pathways. Laura Mitcham explains how rapid assessment of full blood count and C-reactive protein contributed to the success of the project.
Embracing change: trusts collaborate to meet laboratory challenges
Unprecedented demand and a need to embrace a personalised approach to medicine: Penny Pinnock looks at these and other challenges currently facing laboratories, and considers the various financial and technological options available to NHS trusts.
SARS-CoV-2 coronavirus and COVID-19 disease: the pandemic so far
Pathology has faced major challenges this year to detect the SARS-CoV-2 coronavirus, and provide support to COVID-19 patients. Sarah Pitt provides an update on the virology, clinical aspects, testing and epidemiology of this pandemic agent.
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