Sponsors

Assessing critical bleeding: quality and governance standards

Fibrinogen is an essential part of the blood clotting process, and testing aids decision-making in critical care situations, notably post-partum haemorrhage. A novel POCT device now brings this to near-patient settings, but, for such a vital test, accuracy and quality control are key, as Pathology in Practice explains.

Worldwide, post-partum haemorrhage (PPH) is the leading cause of death during childbirth, and declining fibrinogen levels can be the first sign.1,2 The interaction between thrombin and fibrinogen creates fibrin, the insoluble cross-linked polymer needed for successful haemostasis. Fibrinogen is the final essential building block of the clotting process with a significant impact on clinical outcomes when major bleeding occurs (Fig 1).

Against this background, it should be no surprise that the assessment of coagulation status, and fibrinogen testing in particular, is a prime candidate for the application of point-of-care testing (POCT).3 This provides a number of benefits both for patients and the healthcare service in general, as it aids clinical decision-making when clinicians are faced with critical haemorrhage, resulting in the need for immediate patient management and treatment.2

Recently, leading haemostasis company Diagnostica Stago launched qLabs FIB, a novel POC system for monitoring functional fibrinogen. This gained UK Medical Device Regulation (MDR) approval as an in vitro diagnostic device in September 2022 (Fig 2). 

Log in or register FREE to read the rest

This story is Premium Content and is only available to registered users. Please log in at the top of the page to view the full text. If you don't already have an account, please register with us completely free of charge.

Latest Issues

The Power to Disrupt - Clinical Diagnostics Expo UK

15 Hatfields
16 September, 2024

Microbe Conference 2024

Crowne Plaza Hotel, Sheffield, UK
20-22 September, 2024

Cardiac Marker Dialogues: Cardiac Biomarkers in Real Time – Experiences and Opportunities

Hilton Glasgow, 1 William Street, Glasgow, Scotland, G3 8HT
26-27 September, 2024

The British Association for Cytopathology Annual Scientific Meeting

Aztec Hotel and Spa, Bristol, BS32 4TS
18 October, 2024

UK NEQAS: Navigating Quality Standards in Point of Care Testing

The Hyatt Regency Hotel, Birmingham, UK
23 October, 2024