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A pain in the gut: a look at the diagnosis of gastrointestinal disease

Accurate diagnosis of GI disease is fundamental for appropriate patient management. Focusing on four common diseases, Carolyne Horner describes how a selection of commercial kits may supplement diagnostic methods and support diagnosis.

In simple terms, the gastrointestinal (GI) tract is a flexible tube with an entrance at one end (mouth), a sphincter-controlled exit (anus) at the other, with a series of organs (pharynx, oesophagus, stomach, small intestine and large intestine) in between. Add to that the closely regulated function of the pancreas, gall bladder and liver, the enteric nervous system, not to mention the 100 trillion microorganisms that form the teeming intestinal microbiota,1 and the GI tract emerges as a complex, interacting system associated with a correspondingly complex range of disorders and diseases.

Tummy troubles

Diseases of the GI tract are diverse, ranging from acute foodborne infection, chronic inflammatory bowel disease (IBD), to life-threatening colorectal cancer (Fig 1). Gastrointestinal disease may be mild and transitory causing a minor inconvenience, or may be severe and affect the quality of life of the patient on a daily basis, or may even require life-changing surgery, such as removal of a section of colon and the need for a stoma bag.

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Upcoming Events

Pathology Horizons 2024

MacDonald Bath Spa Hotel, Bath
18-20 April, 2024

ECCMID 2024 - European Congress of Clinical Microbiology and Infectious Diseases

Fira Gran Via, 08038 Barcelona, Spain
27-30 April 2024

British Society for Microbial Technology Annual Microbiology Conference

UK Health Security Agency, Colindale, London
2 May 2024

EQA Reports: Interpreting Key Information & Troubleshooting Tips

ONLINE - Zoom
Thursday 16th May 2024

Participants’ Meeting: UK NEQAS Immunology, Immunochemistry & Allergy

Sheffield Hallam University, City Campus, Howard Street, Sheffield
24th May 2024

Med-Tech Innovation Expo

NEC, Birmingham
5-6 June, 2024

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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