ARUP Laboratories has expanded its AI-augmented screening tool for the detection of human gastrointestinal parasites to include wet-mount slides. With this expansion, ARUP Laboratories will become the first and only laboratory to apply AI-augmented screening to the entire ova and parasite testing process.
"By utilising an AI-augmented screening process, we have seen a significant increase in sensitivity and diagnostic yield, said Marc Couturier, PhD. Couturier, who formerly served as the head of clinical operations for Clinical Microbiology and Immunology and as the medical director of Emerging Public Health Crises, Parasitology and Fecal Testing, and Infectious Disease Antigen Testing, has led the development of AI-augmented parasitology screening at ARUP. “The screening tool minimises human error and detects ova and parasites that may otherwise be missed, which improves clinical diagnoses and ultimately treatment for patients who are affected."
Gastrointestinal parasite detection by traditional microscopy presents several challenges. The process is manual and time consuming, places significant burden and stress on laboratory staff, and requires extensive staff training and experience. The AI-augmented screening tool uses scanned images to screen and eliminate negative specimens, which allows staff to focus their time and expertise on the identification of positive specimens. The tool also reduces ergonomic stressors on laboratory staff, decreases turnaround time, increases capacity, and improves patient care.
This development is a continuation of ARUP's leadership in the technological advancement of ova and parasite testing. In 2019, ARUP launched the world's first AI-augmented screening tool for the detection of gastrointestinal parasites that included trichrome stains.
Since the initial launch in 2019, the AI-augmented screening tool has demonstrated a five-fold increase in the limit of detection and a positivity rate that has nearly doubled. This increased sensitivity improves positive detection of parasites to better inform clinical decisions and treatments.
ARUP Laboratories developed the AI solution in partnership with Techcyte, a leading company in the development of anatomic and clinical pathology artificial intelligence solutions.
"Before our launch of an AI-augmented screening tool, technological advancements in the detection of gastrointestinal parasites have been stagnant, really, since the invention of the microscope," said Adam Barker PhD, ARUP Chief Operations Officer and Medical Director of Next Generation Sequencing (NGS) Infectious Disease, Research and Development Special Operations, Reagent Laboratory, Technology Transfer, and Transportation. "Now, ARUP is setting a new standard for ova and parasite testing that will not only improve our diagnostic capabilities but also enhance patient care."
The parasitology AI-augmented screening tool will be implemented in ARUP's parasitology laboratory in early 2025.