Sphere Fluidics, a leading provider of innovative microfluidics-based solutions for single-cell analysis and isolation, has announced the launch of Cyto-Cellect Fc Fusion, a novel assay designed to accelerate cell line development for Fc fusion manufacturing.
Cyto-Cellect Fc Fusion is a robust, single-cell bioassay that leverages a novel fluorescent detection method and enables high-throughput detection of Fc fusion protein production from single cells in picodroplets. This assay is optimised for detection of Fc fusion proteins, an important class of biologic therapeutics. The new assay provides a sensitive and specific approach to detect these proteins in a single-cell format, allowing for high-throughput screening and rapid identification of cells producing high levels of Fc fusion proteins.
The Cyto-Cellect Fc Fusion assay kit expands on Sphere Fluidics’ existing portfolio of Cyto-Cellect assays, offering unique capabilities for researchers to streamline their workflows in cell line development. The assay is fully compatible with Sphere’s new Cyto-Mine Chroma platform as well as the first generation Cyto-Mine instrument, allowing for seamless integration into existing workflows.
The Cyto-Mine Chroma platform combines single-cell dispensing, sorting, imaging, and clone verification in one automated, bench-top system. Powered by Sphere Fluidics’ patented microfluidic picodroplet technology, the Cyto-Mine Chroma platform enables the rapid screening of millions of cells with unparalleled throughput, accelerating research in areas such as antibody discovery, cell line development, and cell engineering. The platforms’ high-throughput capabilities, combined with the Cyto-Cellect Fc Fusion assay, make it an ideal solution for researchers working on recombinant protein development and therapeutic applications.
Richard Hammond, Chief Technology Officer at Sphere Fluidics, commented: “The ability to support Fc Fusion programs with an optimised assay for our Cyto-Mine platforms is an exciting step for Sphere Fluidics. It is the latest product of an ongoing initiative to rapidly expand our menu of assay kits, enabling our customers to utilise Cyto-Mine across a wide range of Cell Line Development and Antibody Discovery projects.”
Cyto-Cellect Fc Fusion is now available for order and can be used with the Cyto-Mine and Cyto-Mine Chroma platforms for high-throughput single-cell screening and analysis.