Sponsors

Bio-Rad extends range of anti-biotherapeutic antibodies

Bio-Rad Laboratories has launched four new anti-idiotypic antibodies to the following drugs: atezolizumab (Tecentriq), avelumab (Bavencio), obinutuzumab (Gazyvaro), and ocrelizumab (Ocrevus), extending its range of anti-biotherapeutic antibodies. The company also introduced its anti-monomethyl auristatin E (MMAE) biotherapeutic antibody range for bioanalysis.

Bio-Rad’s range of ready-made anti-biotherapeutic antibodies enables the development of robust and reliable bioanalytical assays against marketed biologic drugs. The new anti-idiotypic antibodies are suitable for pharmacokinetic (PK) and antidrug-antibody assays for atezolizumab, avelumab, obinutuzumab, and ocrelizumab, enabling therapeutic drug monitoring for innovator and biosimilar products.

The anti-MMAE antibody range supports bioanalysis of antibody-drug conjugates (ADCs) carrying MMAE as payload. MMAE is a potent antimitotic agent that inhibits cell division. Due to its toxicity, MMAE is not used as a drug itself, but instead forms the payload component of ADCs. Bio-Rad’s new anti-MMAE biotherapeutic antibodies enable the development of sensitive assays for both ADCs incorporating the toxin, or the toxin itself.

“Bio-Rad’s extensive range of anti-biotherapeutic antibodies offers an effective solution to drug-specific bioanalytical assay development, enabling design of selective, sensitive, and reliable PK and ADA assays,” said John Cardone, Marketing Manager, Life Science Group, Bio-Rad. “Introduction of the new drug-specific and MMAE anti-biotherapeutic antibodies further expands the utility of our market-leading portfolio of over 200 anti-idiotypic antibodies, providing our customers with new and innovative bioanalysis tools to accelerate antibody drug discovery.” 

To learn more about Bio-Rad’s anti-idiotypic antibodies, visit www.bio-rad.com/biotherapeutic-antibodies.

 

See more about Bio-Rad Laboratories

Latest Issues

The Festival of Genomics and Biodata

ExCeL, London Docklands,
29-30 January 2025

Microbiology Society Annual Conference 2025

Liverpool Arena and Convention Centre
31 March - 3 April, 2025

BSMT Annual Microbiology Conference

RAF Museum, Hendon, London NW9 5LL
15 May, 2025

Ghent Pathology 2025

ICC Ghent, Belgium
24-26 June, 2025

37th European Congress of Pathology

ACV, Vienna, Austria
6 -10 September, 2025