Improving efficiency in oestradiol testing for rapid IVF support

Testing for oestradiol is a crucial first step in the time-sensitive IVF process. Detailed here are the steps a French-based laboratory was able to take to automate this previously time-consuming and labour-intensive task safely and effectively, while still meeting important deadlines.

 The oestradiol test is a key indicator of the menstrual cycle. In medically assisted fertilisation, this parameter helps clinicians to identify if the impending oocyte is mature enough to be harvested. When the test result is within expected range, everything needs to happen within a 24-hour period. Quick and synchronised actions are necessary to make this possible. Every step is critical - from sampling to test result generation to planning the surgical intervention aimed at increasing the likelihood of a successful pregnancy.

These tests are vital. In France alone, one in 30 children is conceived using assisted reproductive technology (ART) techniques, with in vitro fertilisation (IVF) representing 70% of all ART-conceived babies in France. The first French IVF baby was born in 1982, and since then, the number of in vitro fertilisations has risen continuously and at a remarkably linear rate. The share of babies conceived in vitro has been rising 0.5% every seven to eight years.  

Oestradiol sampling

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