PCR Biosystems has launched Air-Dryable Probe 1-Step Mix, described as a versatile all-in-one, air-dryable 4x RT-qPCR reagent mix for ultra-sensitive detection of RNA and DNA sequences.
With this kit, the performance of the company’s liquid PCR reagents can be brought to dried assay formats using a standard laboratory oven, offering a simpler, faster, and cheaper alternative to lyophilisation (freeze-drying). Now, a larger base of assay kit developers, including smaller organisations with fewer resources, can access the advantages of dried assays — shorter time-to-market, simplified logistics and storage, and significantly reduced costs.
With the new air-dryable kits, drying can be done in just 80 minutes with a simple laboratory oven, without extensive training, and at a much lower cost. As a result, organisations unable to build onsite lyophilisation capabilities can now create high-performance dried assays in-house, with full control over the drying process and quality control steps. As with the company’s lyophilisable mixes, the air-dryable mixes retain performance after reconstitution. Kits also come with the company’s renowned technical support to ensure smooth troubleshooting and optimal results, and free samples are available.
"Dryable reagents are redefining the ease and convenience with which PCR assays are being developed, distributed, and used. Lyophilisation has played a huge part here, but barriers to its adoption have seen smaller companies get left behind." said Alex Wilson, co-founder of PCR Biosystems. "Our air-dryable mixes erode barriers to drying, so even with minimal resources, developers can get superior-quality dried assays to the point of care, efficiently. This is the latest step in our journey to place simple, cost-effective, and high-performing tests within reach of all."
The new kits comprise a glycerol-free 4x qPCR mix with hot start Taq polymerase, dNTPs, MgCl₂ and a blend of excipients for reliable drying without activity loss. A more stable version of UltraScript Reverse Transcriptase and RiboShield™ RNase inhibitor are blended into the mix, providing a more convenient single-tube format. Kits can be used for both RNA and DNA detection for greater versatility, and dried assays are stable for three months at 37°C.
Critically, PCR Biosystems is certified to conform to Quality Management System standard ISO 13485, ensuring full product traceability, and optimum lot-to-lot consistency. Assay developers can therefore be confident in using the new air-dryable kits to create the highest-quality tests.
Free samples can be requested via the webpage below.
https://pcrbio.com/request-an-air-dryable-probe-1-step-mix-sample/