ViroStat has released new parasitic lactate dehydrogenase (pLDH) monoclonal antibodies, which can be powerful immunoassay tools for malaria detection.
These monoclonal antibodies are reactive with Plasmodium falciparum, P. malariae and P. vivax. One pair of these antibodies can detect pLDH from all three species by enzyme-linked immunosorbent assay (ELISA).
Malaria can be caused by several species of the Plasmodium parasite. Parasitic lactate dehydrogenase is found in many Plasmodium species, and levels of this intracellular enzyme are elevated during the blood-stage of infection. Detection of this enzyme in blood is a strong indicator of malaria infection.
The data sheet for these new antibodies can be downloaded from the ViroStat website.