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Vaccine-induced immune thrombotic thrombocytopenia: selected research

This month’s cover story looks at vaccine-induced thrombocytopenia and thrombosis (VITT), a rare side-effect of the ChAdOx1 nCoV-19 adenoviral vector vaccine. The following examples of open-access current research expand on this theme.

COVID-19 vaccine-associated immune thrombosis and thrombocytopenia (VITT): Diagnostic and therapeutic recommendations for a new syndrome

Franchini M, Liumbruno GM, Pezzo M. Eur J Haematol 2021; 107 (2): 173–80. doi: 10.1111/ejh.13665.

Very rare cases of thrombosis associated with thrombocytopenia have occurred following the vaccination with AstraZeneca COVID-19 vaccine. The aim of this concise review is to summarise the current knowledge on the epidemiologic and pathogenic mechanisms of this syndrome named vaccine-associated immune thrombosis and thrombocytopenia (VITT). A practical patient management section will also be dealt with using information available from national and international scientific societies as well as expert panels.

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