The website of Pathology In Practice Magazine

Automated pipetting solutions that assist antibiotic development

INTEGRA is helping in the vital task of tackling antibiotic resistance by providing the liquid-handling tools to help increase throughput and reproducibility in drug development workflows.

The company’s ASSIST PLUS pipetting robot, and VIAFLO 96, VIAFLO 384 and MINI 96 handheld electronic pipettes, meet the needs of early phase drug discovery by offering high-throughput processing of routine pipetting tasks – such as serial dilutions and plate inoculation – without compromising on precision and reproducibility.

Drug discovery requires large-scale screening to assess the activity of novel compounds against various bacteria. Determining crucial parameters – such as the minimum inhibitory concentration (MIC), IC50, EC50 or LD50 – of candidate antibiotics is an essential step in this process, requiring the generation of multiple serial dilutions and several replicates for every compound. Repetitive pipetting tasks are therefore a common feature in the daily activities of drug discovery laboratories, and INTEGRA offers a range of time-saving solutions that relieve staff of this burden. 

INTEGRA’s ASSIST PLUS can be combined with the company’s VOYAGER adjustable tip-spacing pipette to provide an elegant walkaway solution for performing serial dilutions in microplates. This set-up can automate compound transfer and mixing steps – performing them faster and more reliably than manual processing – and allows rapid transfer of compounds or bacterial inoculum from tube formats directly to microplates. Similarly, the VIAFLO 96, VIAFLO 384 or MINI 96 handheld electronic pipettes can be used to perform simultaneous inoculation of every well of a microplate, significantly accelerating assay set-up and eliminating time-associated variability. These innovative pipetting systems, together with other solutions from the INTEGRA portfolio, are helping to alleviate the pipetting bottleneck in antibiotic development, streamlining routine pipetting tasks for more efficient and productive workflows.

 Visit the INTEGRA Biosciences website to learn more.

Upcoming Events

Lab Innovations 2021

NEC, Birmingham
3-4 November 2021

IBMS Biomedical Science Congress 2022

International Convention Centre, Birmingham
14-17 March 2022

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

Upcoming Events

Lab Innovations 2021

NEC, Birmingham
3-4 November 2021

IBMS Biomedical Science Congress 2022

International Convention Centre, Birmingham
14-17 March 2022

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

Step Communications Ltd, Step House, North Farm Road, Tunbridge Wells, Kent TN2 3DR
Tel: 01892 779999 Fax: 01892 616177
www.step-communications.com
© 2021 Step Communications Ltd. Registered in England. Registration Number 3893025