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Telomeres and telomerase: research on the genetic arrow of time

A search of the current scientific literature published in 2021 on this important element of chromosome structure, and its complementary enzyme, illustrates the diverse effects they have in health and disease.

Telomeres: history, health, and hallmarks of aging

Chakravarti D, LaBella KA, DePinho RA. Cell 2021; 184 (2): 306–322. doi: 10.1016/j.cell.2020.12.028. 

The escalating social and economic burden of an ageing world population has placed ageing research at centre stage. The hallmarks of ageing comprise diverse molecular mechanisms and cellular systems that are interrelated and act in concert to drive the ageing process.

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