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Helicobacter pylori: research in the open-access literature

A selection of research into Helicobacter pylori, which complements the work reported by Coleman and Davies in the February 2021 issue of Pathology in Practice.

Biofilm formation by Helicobacter pylori and its involvement for antibiotic resistance

Yonezawa H, Osaki T, Kamiya S. Biomed Res Int 2015; 2015: 914791. doi: 10.1155/2015/914791. 

Bacterial biofilms are communities of microorganisms attached to a surface. Biofilm formation is critical not only for environmental survival but also for successful infection.    Helicobacter pylori is one of the most common causes of bacterial infection in humans. Some studies demonstrated that this microorganism has biofilm forming ability in the environment and on human gastric mucosal epithelium, as well as on in vitro abiotic surfaces. In the environment, H. pylori could be embedded in drinking water biofilms through water distribution systems in developed and developing countries so that the drinking water may serve as a reservoir for H. pylori infection.

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