Although often taken for granted, modern glass microscope slides, their characteristics and features can have an impact on test performance, diagnosis and laboratory workflow. Here, Mark Wilson looks at some of the features offered by Epredia products.
If you read any of the standard histopathology text books that are commonly available you will see chapters on microscopy, processing, staining, immunohistochemistry (IHC) and other specialised techniques, but very little if any mention of what must be the most widely used consumable in routine histopathology, the standard microscope slide. What is written usually just refers to the size and thickness, with no mention of what type of slide can be used for different applications, or the technology required to manufacture them.
In the 19th century, many scientific advancements were made in pathology. These included more regular use of glass microscope slides, the development of high-quality microscopes, the use of paraffin wax for infiltration, and the creation of formalin. These developments, along with invention of the microtome, allowed histologists to prepare 5 µm sections of tissue. This all helped to achieve a greater understanding of histopathology and anatomy.
While these developments in science were occurring, in Romont, a small town in Switzerland, the local authorities found that they had a surplus of electricity due to a new hydro-electric installation. It was decided that they would open a glass works factory using the cheap electricity available, and build what would be the world’s first electric glass furnace.
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