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CBC-O: how haematology systems aid investigation of a raised MCHC

Modern analyser systems provide cutting-edge support to the haematology laboratory, the latest prime example of which is the benefits provided by equipment and algorithms in the investigation of the cause of a raised mean corpuscular haemoglobin concentration.

The complete blood count (CBC), also termed the full blood count (FBC), is a common test performed on automated haematology equipment to provide an evaluation of numerous aspects of the cellular components of circulating blood, namely the diagnostic parameters of white blood cells (WBCs), red blood cells (RBCs) and platelets (PLT). The interpretation and validation of FBC results and the handling of abnormal or suspicious results can prove a vital contribution to the clinical interpretation and therefore the patient diagnosis and/or treatment.1

An example of such challenging results are cases in which an elevated mean corpuscular haemoglobin concentration (MCHC) is identified, often erroneously as a result of one of many possible sample interferences. With the introduction of the CBC-O concept, Sysmex has developed a standardised method of investigating such samples. Using the XN-Series RET channel technology, CBC-O indicates the cause of an increased MCHC and offers users the most appropriate corrective actions for each specific sample, reducing the manual efforts required. With CBC-O, it is possible to report optimised CBC results for every sample – faster and with more confidence.

CBC-O (Optical): concept

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