With lower temperatures and shorter periods of daylight at this time of year, norovirus, the so-called ‘winter vomiting bug’, is set to revisit the hospital setting, bringing with it cases of vomiting and diarrhoea. The following items of research interest are all available via PubMed as free PMC articles.
Simultaneous immunization with multivalent norovirus VLPs induces better protective immune responses to norovirus than sequential immunization
Malm M, Vesikari T, Blazevic V. Viruses 2019 Nov 2; 11 (11). pii: E1018. doi: 10.3390/v11111018.
Human noroviruses (NoVs) are a genetically diverse, constantly evolving group of viruses. Here, the authors studied the effect of NoV pre-existing immunity on the success of NoV vaccinations with genetically close and distant genotypes. A sequential immunisation as an alternative approach to multivalent NoV virus-like particle (VLP) vaccine was investigated.
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