First appearing over four decades ago, the viral haemorrhagic disease that takes its name from a river in the Democratic Republic of Congo continues to blight the region of sub-Saharan Africa. The following selection of free-to-access papers found in the recent literature provide a flavour of current research efforts.
Evaluation of diagnostic performance of three indirect enzyme-linked immunosorbent assays for the detection of IgG antibodies to Ebola virus in human sera
Paweska JT, Moolla N, Storm N et al. Viruses 2019 Jul 24;11 (8). pii: E678. doi: 10.3390/v11080678.
Filovirus serological diagnosis and epidemiological investigations are hampered due to the unavailability of validated immunoassays. Diagnostic performance of three indirect enzyme-linked immunosorbent assays (I-ELISA) was evaluated for the detection of IgG antibody to Ebola virus (EBOV) in human sera. One I-ELISA was based on a whole EBOV antigen (WAg) and two utilised recombinant nucleocapsid (NP) and glycoproteins (GP), respectively.
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