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Leukaemia and lymphoma: an example of how flow cytometry aids diagnosis

An expanded portfolio of standardised in vitro diagnostic reagents has enhanced the work of the clinical flow cytometry laboratory, as recently published examples in a Beckman Coulter ClearLLab Casebook illustrate.

Flow cytometric immunophenotyping (FCI) techniques are an important element in aiding the diagnosis and follow-up of leukaemia and non-Hodgkin’s lymphoma (NHL). “The overriding benefit over immunohistochemistry (IHC) techniques is the ability to assess numerous markers simultaneously,” says Jeannine Holden, Chief Medical Officer and Vice President of Scientific and Medical Affairs at Beckman Coulter.

. Flow cytometry’s ability to show even subtle differences in antigen density makes it possible to distinguish and characterise aberrant cells that may be present in minute quantities.1 In Europe, flow cytometry is already used for patients presenting with disease in the bone marrow and/or peripheral blood, and increasingly used to study lymph nodes

Characterising normal and aberrant cells

Evidence of flow cytometry’s ability to characterise both normal and aberrant cells was further

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International Convention Centre, Birmingham
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