Hepatitis C was first discovered in the 1980s and known initially as non-A, non-B hepatitis. It was identified properly in 1989, and in 1991 a screening process was developed making it possible to detect hepatitis C virus in blood samples. As a relatively new disease, there remain many aspects of hepatitis C which are yet to be fully understood, as the following selection of research efforts illustrate.
Hepatitis C virus infection and chronic renal disease: a review
Goel A, Bhadauria DS, Aggarwal R. Indian J Gastroenterol 2018 Dec 18. doi: 10.1007/s12664-018-0920-3 (Epub ahead of print).
Hepatitis C virus (HCV) is a parenterally-transmitted hepatotropic virus that often causes chronic infection, which can progress to cirrhosis and hepatocellular carcinoma. Development of highly effective direct-acting antiviral agents (DAAs) has led to a paradigm change in the treatment of HCV infection over the last four to five years. Patients with chronic kidney disease (CKD) are at a higher risk of acquiring HCV infection. In these patients, diagnosis of HCV infection, assessment of the consequent liver disease and management of HCV infection pose some specific problems.
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