Research in the medical laboratory provides opportunities both for the seasoned professional and also those in the early stages of their career. The work reported below focuses first on guidance provided to aid the establishment of defined reference intervals, and second reflects on the implementation and use of large, whole-mount sections and their value in the histopathological assessment of colorectal cancer.
Ferritin and vitamin B12 reference intervals: a modified Hoffmann’s approach
Establishing defined reference intervals in the laboratory can prove difficult. Here, Agata Sobczyńska-Malefora, Nadia Munim, Martin Crook, Dominic Harrington and Alexander Katayev provide some guidance.
Age and/or gender-specific population-based reference intervals (RIs) are rarely available or are difficult to establish in clinical laboratories. With an increased focus on the between-method standardisation and harmonisation of test results, the development of universal RIs for standardised and harmonised assays may help laboratories to improve patient care.
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