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Ceftolozane/tazobactam test discs

Mast has launched a new addition to the Mastdiscs stock cartridge range, Ceftolozane/tazobactam 30/10 (C/T40C). Merck has launched the intravenous antibiotic Zerbaxa (ceftolozane/tazobactam) in the UK for the treatment of complicated intra-abdominal infections, acute pyelonephritis and complicated urinary tract infections in nosocominal environments.

Ceftolozane/tazobactam provides an alternative to carbapenems for the treatment of extended-spectrum beta-lactamase (ESBL)-producing organisms. Overuse of carbapenems has been known to contribute to the global dissemination of resistance. Professor David Livermore (University of East Anglia) said: “Ceftolozane/tazobactam is very important because it’s a new antibiotic that treats Gram-negative infections, where a lot of resistance problems are now accumulating. Its activity against Pseudomonas is especially important.

“It overcomes both the major mechanisms (efflux and inactivation) that often compromise other cephalosporins against this difficult species. As always, there’s more to be done, more clinical trials are needed in further settings, particularly those where you find most of the difficult Pseudomonas strains.”  Additionally, EUCAST released clinical breakpoints in January for antibiotic susceptibility test discs for ceftolozane/tazobatam 30/10 (C/T40C). These are available from Mast in a stock cartridge format, each pack containing 5 x 50 discs and compatible with Mast’s new DiscMaster 4 dispenser (MDD64).

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Upcoming Events

Pathology Horizons 2024

MacDonald Bath Spa Hotel, Bath
18-20 April, 2024

Diagnostics North East Conference 2024

The Catalyst, Newcastle upon Tyne
19 April, 2024

ECCMID 2024 - European Congress of Clinical Microbiology and Infectious Diseases

Fira Gran Via, 08038 Barcelona, Spain
27-30 April 2024

British Society for Microbial Technology Annual Microbiology Conference

UK Health Security Agency, Colindale, London
2 May 2024

EQA Reports: Interpreting Key Information & Troubleshooting Tips

ONLINE - Zoom
Thursday 16th May 2024

Participants’ Meeting: UK NEQAS Immunology, Immunochemistry & Allergy

Sheffield Hallam University, City Campus, Howard Street, Sheffield
24th May 2024

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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