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Early sepsis detection: the role of improved procalcitonin testing

The early detection of sepsis is vital in order to provide an appropriate patient treatment plan. Here, Wayne Kipp provides an overview of the condition and looks at the merits of the latest procalcitonin assay.

www.en.wikipedia.org Jmol Development Team Public domain

According to the Global Sepsis Alliance, sepsis affects over 26 million people each year and is the largest killer of children and newborns worldwide. Despite advances in knowledge, sepsis continues to increase at an annual rate of 8-13%, calling for a greater improvement in both the diagnosis and treatment of severe bacterial infections.

Procalcitonin (PCT) is a useful marker for bacterial infection and therefore sepsis, and proves beneficial in determining whether a patient is suffering from a bacterial or viral infection. This distinction is useful in deciding between treatment options and helps to ensure that antibiotics are only given when a bacterial infection is indicated.

Recent advances in the accuracy, speed and accessibility of PCT tests will help to improve the chances of identifying sepsis early in order to direct the correct course of treatment. For example, the Stanbio PCT LiquiColor assay (EKF Diagnostics, Cardiff) incorporates a methodology that provides quick and accurate results, as well as a cost-effective implementation that does not require dedicated instrumentation.

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Upcoming Events

Pathology Horizons 2024

MacDonald Bath Spa Hotel, Bath
18-20 April, 2024

Diagnostics North East Conference 2024

The Catalyst, Newcastle upon Tyne
19 April, 2024

ECCMID 2024 - European Congress of Clinical Microbiology and Infectious Diseases

Fira Gran Via, 08038 Barcelona, Spain
27-30 April 2024

British Society for Microbial Technology Annual Microbiology Conference

UK Health Security Agency, Colindale, London
2 May 2024

EQA Reports: Interpreting Key Information & Troubleshooting Tips

ONLINE - Zoom
Thursday 16th May 2024

Participants’ Meeting: UK NEQAS Immunology, Immunochemistry & Allergy

Sheffield Hallam University, City Campus, Howard Street, Sheffield
24th May 2024

Access the latest issue of Pathology In Practice on your mobile device together with an archive of back issues.

Download the FREE Pathology In Practice app from your device's App store

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