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New Carl Zeiss software speeds vaccine research

Software designed to speed up tumour, AIDS and vaccine research is being released by Carl Zeiss. The new KS ELISpot application combines with Zeiss microscope systems to make ELISpot (enzyme-linked immunosorbent spot) reading faster, more sensitive and more convenient, and also enables fluorescence ELISpot evaluation.

The KS ELISpot compact, based around the Zeiss Stemi 2000 C stereomicroscopes, will read and evaluate the results of a 96-well microplate in less than four minutes and is ideally suited to the routine laboratory. For the research laboratory, the Axio Imager-based KS ELISpot will distinguish spots as small as two microns and, combined with the AxioCam camera and suitable filters, enables fluorescence ELISpot evaluation.

Originally developed to enumerate B cells secreting antigen-specific antibodies, ELISpot has been adapted for various tasks, especially the identification and enumeration of cytokine-producing cells at the single-cell level, where it allows visualisation of the secretory product of individual activated or responding cells.

www.zeiss.co.uk

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