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Health warnings in small dense packages

Randox has released a simple test for the fully automated, quantitative detection of the small dense form of low-density lipoprotein (sd LDL). Research into LDL cholesterol and the implications for risk of cardiovascular disease (CVD) has identified two LDL subtypes, small dense LDL and large buoyant LDL. Genetic and nutritional factors affect the size of the LDL particles.

The small, more atherogenic LDL particles penetrate the inner layer of the coronary arteries more easily, are more susceptible to oxidisation and they bind proteoglycans, all of which increases the risk of CVD. Determination of sd LDL in a patient sample can help clinicians profile higher risk individuals and improve prognosis through adjusted treatment.

Randox has widened the range of lipoprotein tests available by releasing a simple method for sd LDL. It can be run on an automated clinical chemistry analyser, and will give results in 30 minutes. This method supersedes the current electrophoresis method, which assesses the pattern of LDL to identify type A (predominantly large LDL) or type B (predominantly small LDL). The Randox sd LDL test is fully automated, saving time and labour costs, and gives a quantitative sd LDL result.

www.randox.com

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