FEATURE ARTICLES

With the passage of an unseasonably mild autumn and the onset of winter, thoughts turn to what infections the dormant season has in store for the susceptible among us. Viral infections are high on the list of things of which to be wary, and laboratories, with a little help from Oxoid, must be as vigilant as ever in an attempt to identify these agents promptly.

Hospital-acquired infection is of increasing concern in the health service, and the spectre of MRSA is now being joined by other, equally problematic infections. However, new technology from Acolyte Biomedica has joined the fight and promises to expedite detection and antibiotic susceptibility testing, directly from clinical specimens.

Increasingly, workflow efficiency is seen as the way forward in dealing with ever-expanding workload, and tracks linking individual analysers are becoming a more common sight in the laboratory. Here, biomedical scientists from Basingstoke in Hampshire share their experiences of a very successful implementation.

Computer technology has supported the work of pathology for longer than that of any other healthcare group, yet Connecting for Health appears to have forgotten about this vital area of medicine. Here, Jem Rashbass puts forward the case for an appropriately resourced pathology IT programme.

The battle against healthcare-acquired infections such as methicillin-resistant Staphylococcus aureus and extended spectrum ▀-lactamase-producing organisms continues with a need for high-level leadership and support, the Infection Control Nurses Association Conference, held recently in Brighton, was told. A comprehensive report of the proceedings follows.

Such has been the response to the CellNass off-site storage service, launched in 2003, that cellular pathology specialist CellPath has had to build a new facility to keep up with demand from across England and Wales.

Examination of bone sections for abnormalities is helping to define mechanisms of bone loss in untreated and treated osteoporosis, but imaging large bone sections can prove difficult. Here, Ana Maria Caballero-Alias discusses some of the issues surrounding imaging this type of section and how digital systems are overcoming some of these problems.

Advances in stem cell technology have prompted attempts to remove legal obstacles arising from differences in patentability standards in national legislation and case law across Europe. Here, SiΓn Gill explains the complexities of patent protection and how they relate to this emotive subject.

Bacterial sepsis is a major cause of neonatal morbidity and mortality, particularly in preterm babies. Can a new rapid cytokine test improve diagnosis over use of C-reactive protein alone and help reduce unnecessary antibiotic use?

The new UniCel DxC 880i from Beckman Coulter is designed for high-throughput workstation consolidation, as Jag Grewal, the companyÆs marketing manager for Northern Europe, explains.

From porphyrin analysis to textile sun protection factor measurement, use of spectrophotometers from Norfolk-based company Camspec has achieved global utility in routine and research applications in the past 20 years.

The current drive towards greater automation in pathology should be measured against a range of important factors that need to be considered carefully. Here, Alistair Forrest goes into some detail and provides an example of a successful implementation.

The use of glass microscope slides across pathology is largely taken for granted, but the technology that produces these ubiquitous laboratory consumables varies considerably, depending on which part of the world you happen to explore. Here, Andrew Cuthbert peers through the looking glass at slide production worldwide.

Temperature plays a vital role in polymerase chain reaction methodology. Thus, it is important to verify that thermal cyclers used in the technique are functioning properly. Here, Tom Hendrix, Marc Verblakt and Roger Pierik report on a study of cycler performance and on a validation service.

PathLore was established in 2001 to provide an alternative private sector model for cellular pathology support and provision in the UK. It was designed to meet emerging and anticipated future needs and those of other branches of pathology. Here, Professor Ian O Ellis gives an historical perspective and provides an overview of progress so far.

Telepathology provides a range of benefits in cellular pathology, and at the heart of this technology are digital pathology systems and so-called virtual microscopy. Paul Cormack provides an overview of progress in this exciting field of laboratory medicine.

Agenda for Change and the latest government pathology review are evolutionary pressures on pathology the effect of which will only become fully apparent with the passage of time. However, forewarned is forearmed, so Pathology û the real agenda will inform, update and advise.

Tissue processing changed little over the course of the last century until the introduction of microwave equipment into histopathology. Now, the technology that revolutionised work in the kitchen appears set to do the same in one of the oldest disciplines in pathology, as Sue Wollington explains.

Clinical Diagnostics and Water, Environmental and Industrial Analysis are the two divisions that comprise Manchester-based company Labmedics. Now, two decades of expertise has resulted in an international reputation.

The importance of erythrocyte sedimentation rate as a laboratory investigation is often overlooked, but it is one that clinicians use to judge the efficacy of certain forms of treatment. Thus, confidence in the test requires accurate control, as Peter Hooper explains.